Particularly in early fall, a trip to the White Mountains for foliage viewing is rewarding. Boston, Vermont and the Southern Maine Coast are not too far.
A trip down State Route 101 heading west will bring you to many of the type of small towns that NH and New England are famous for including Amherst, Milford, Wilton, and Peterborough. Past Wilton, the road becomes more windy and scenic but is still a major east-west thoroughfare. The route ends in Keene about an hour away.